2014년 11월 30일 일요일

DNA Transcription

Act I: Initiation
-proteins, transcription factors recognize the promotor "TATA box" and bind to the promotor.
-RNA polymerase II binds to transcription factors and creates a transcription initiation complex.
-Polymerase II starts transcription.

Act II: Elongation
-RNA, same as DNA, grows from 5' to 3'
-RNA polymerase untwists double helix and adds nucleotides to the 3' end of the growing strand.
-Uracil replaces thymine
-Strand that is anti-parallel from the template =antisense
-Strand that is similar to coding =sense
-direction of transcription, from upstream: before gene to downstream: after gene

Act III: Termination
-reaches "AAAAUAAA"



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